The Signaling Pathways Project is a multi-omics knowledgebase based upon public, manually curated transcriptomic and cistromic (ChIP-Seq) datasets involving genetic and small molecule manipulations of…
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Medicine & Health Global Child Health: From Birth to Adolescence and BeyondView Collection
In 2000, the UN adopted the Millennium Development Goals (MDGs), which were intended to address key determinants of human health and welfare, including poverty, hunger, and disease. One of the MDGs…
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Medicine & Health Trafficking, Exploitation and HealthView Collection
The health consequences of human trafficking and exploitation are sufficiently prevalent and damaging that they comprise a public health problem of global magnitude. This PLOS Collection offers…
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Medicine & Health Regulatory Harmonization CollectionView Collection
While regulation of medicines is a key pillar of any health system assuring access to quality medicines, an unoptimized regulatory system is a barrier to access. Over the last 8 years the East African…
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Medicine & Health Advances in Clinical Trial Design for Development of New Treatments for TuberculosisView Collection
With recent opportunities to test combinations of new and repurposed drugs for the treatment of TB, new questions arise for optimal clinical trial design. To address these, in March 2018 WHO organized…
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Medicine & Health High-Quality Health SystemsView Collection
High quality health care will be critical to attaining the Sustainable Development Goals in low- and middle income countries. However, little is known on levels of quality and its distribution within…
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collection Refugee and Migrant HealthView Collection
At the 72nd World Health Assembly held during May 20–28 of this year in Geneva, Switzerland, a very welcome global action plan was agreed which seeks to establish a “framework of…
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collection Substance Use, Misuse, and Dependence: Prevention and TreatmentView Collection
Substance use and misuse affect people worldwide, of all ages and from all walks of life, resulting in a substantial burden of ill health and mortality, and presenting big challenges in prevention and…
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Medicine & Health Machine Learning in Health and BiomedicineView Collection
Modern statistical modeling techniques—often called machine learning—are posited as a transformative force for human health. High-profile reports of diagnostic success demonstrate…
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Medicine & Health WHO Estimates of the Global Burden of Foodborne DiseasesView Collection
Illness and death from diseases caused by contaminated food are a constant threat to public health and a significant impediment to socio-economic development worldwide. To measure the global and…
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Medicine & Health Voluntary Medical Male Circumcision for HIV Prevention: New Mathematical Models for Prioritizing Sub-Populations by Age & GeographyView Collection
This PLOS Collection features new mathematical models that can help country decision-makers examine the potential effects of targeting sub-populations for voluntary medical male circumcision services…