The Signaling Pathways Project is a multi-omics knowledgebase based upon public, manually curated transcriptomic and cistromic (ChIP-Seq) datasets involving genetic and small molecule manipulations of…
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Biology & Life Sciences Bringing data to decision making for conservation and biodiversity
Translating conservation and biodiversity research from the field into the real world is a complex problem. This collection discusses issues around economics, policy, and how to do research that…
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Biology & Life Sciences PLOS Biology 20th Anniversary
As PLOS Biology turns 20 years old, we are celebrating two decades of publishing high-impact life sciences research at the forefront of open science. This collection contains articles that look back…
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Biology & Life Sciences Mendel’s legacy in modern genetics
The collection draws on the opinion of experts in the field of genetics, who look back at Mendel’s original research and examine how well it stands up to modern views on genetics, and how it has…
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Biology & Life Sciences Triple drug (IDA) mass drug administration for elimination of lymphatic filariasis
This collection reports results of clinical trials and community studies of the safety, efficacy, and acceptability of the triple drug regimen IDA (ivermectin plus DEC and Albendazole) as a mass drug…
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Biology & Life Sciences Modeling Cell Proliferation and the Cell Microenvironment
Cells use elaborate mechanisms to sense a variety of mechanical and biochemical cues in their environment, to integrate this information, and to generate coherent adaptive responses. A more complete…
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Biology & Life Sciences Domestic Animal Genetics
Domestication of wild animal and plant species may be considered the largest genetic experiment in human history. Human selection for specific traits and targeted breeding over hundreds or thousands…
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Biology & Life Sciences Animal Welfare
Humans have a responsibility to ensure that animals under their care are treated with respect and dignity. Research on animal welfare is crucial to improve the quality of life experienced by animals…
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Biology & Life Sciences Stable Isotopes
The use of stable isotopes as an analytical tool has been invaluable for a wide variety of scientific disciplines. Researchers in fields ranging from palaeooceanography to anthropology have utilized…
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Biology & Life Sciences Health & Health Care in Gender Diverse Communities
The approach to health care for trans and gender diverse individuals is evolving in response to expanding knowledge of the needs in these communities, as well as a growing understanding of the…