At PLOS Pathogens we publish outstanding research on pathogenic organisms including bacteria, fungi, parasites, prions and viruses. Each year, we celebrate the impact our authors have had and share…

Stem cells bring hope to revolutionize biomedical fields given their potential to give rise to any cell type in the body. The papers included in this collection reflect the interdisciplinary nature of…

The strict regulation of the microenvironment by the blood-brain barrier is a key component of central nervous system function. Changes in the structure and function of this unique and dynamic…

The Signaling Pathways Project is a multi-omics knowledgebase based upon public, manually curated transcriptomic and cistromic (ChIP-Seq) datasets involving genetic and small molecule manipulations of…

From binding and altering signaling cascades at the cell surface, to membrane penetration and hijacking of intracellular host membranes, microbes and their toxins interact with host cell membranes in…

The past decade has seen a dramatic increase in global attention to neglected tropical diseases, with remarkable momentum in policy, programs, funding, and research. As we look to the future, it is…

The History of Marine Animal Populations (HMAP) is a global research initiative to study the past ocean life and human interaction with the sea, and is part of the global Census of Marine Life. About…

The 14th Great Lakes Bioinformatics Conference 2019 (GLBIO) took place at the University of Wisconsin at Madison from May 19th to 22nd. The conference was organized by the Great Lakes Bioinformatics…

This collection of papers highlights research performed under the auspices of the Natural Geography in Shore Areas (NaGISA) project, a component of the Census of Marine Life program. NaGISA is a…

A commonly held view is that Modern Synthesis furnished a general, unified theory of evolution, and that more recent findings about microbes show that this theory is false in important ways and must…