PLOS Computational Biology is home to research on living systems at all scales—from molecules and cells, to patient populations and ecosystems—through the application of computational…

PLOS Genetics is home to high-quality research in Genetics and Genomics, including human studies and model organisms . Each year, we celebrate the impact our authors have had in these fields and share…

PLOS NTDs is home to leading research on the world’s most neglected tropical diseases. Each year, we celebrate the impact our authors have had in these fields and share out the body of work…

The work of Denise Barlow revolutionised the field of epigenetics. She spent the majority of her career identifying and studying the mechanistic regulation of the Igf2r imprinted gene cluster and as a…

At PLOS Pathogens we publish outstanding research on pathogenic organisms including bacteria, fungi, parasites, prions and viruses. Each year, we celebrate the impact our authors have had and share…

Stem cells bring hope to revolutionize biomedical fields given their potential to give rise to any cell type in the body. The papers included in this collection reflect the interdisciplinary nature of…

The strict regulation of the microenvironment by the blood-brain barrier is a key component of central nervous system function. Changes in the structure and function of this unique and dynamic…

The Signaling Pathways Project is a multi-omics knowledgebase based upon public, manually curated transcriptomic and cistromic (ChIP-Seq) datasets involving genetic and small molecule manipulations of…

From binding and altering signaling cascades at the cell surface, to membrane penetration and hijacking of intracellular host membranes, microbes and their toxins interact with host cell membranes in…

The past decade has seen a dramatic increase in global attention to neglected tropical diseases, with remarkable momentum in policy, programs, funding, and research. As we look to the future, it is…