The Signaling Pathways Project is a multi-omics knowledgebase based upon public, manually curated transcriptomic and cistromic (ChIP-Seq) datasets involving genetic and small molecule manipulations of…
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Medicine & Health Neglected Populations: Decreasing Inequalities & Improving Measurement in Maternal Health
In order to address the need to reduce inequalities and showcase necessary measurement improvements to uncover them, the Maternal Health Task Force (MHTF) is partnering for the fourth time with PLOS…
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Medicine & Health Non-Communicable Diseases and Maternal Health Around the Globe
Non-communicable diseases (NCDs) account for almost 65% of women’s deaths around the globe, and three quarters of women’s deaths caused by NCDs occur in low- and middle-income countries…
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Medicine & Health Replication of influential studies evaluating interventions for HIV prevention and treatment
Three decades of work on HIV prevention and treatment have yielded effective biomedical, behavioral, social, and structural interventions in controlled trials. Few of these have been adopted at a…
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Medicine & Health PLOS Medicine’s 15th Anniversary
In October 2019, PLOS Medicine celebrates its 15th year of publishing excellent medical research. To celebrate, the PLOS Medicine team and several editorial board members have reflected upon the last…
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Biology & Life Sciences WorldLeish-6
There are currently 350 million people in 98 countries at risk of developing leishmaniasis, the vector-borne parasitic disease caused by various species of trypanosomatid protozoa in the genus of…
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Medicine & Health Challenges in Environmental Health: Closing the Gap between Evidence and Regulations
Over 80,000 chemicals are used in commerce in the United States, and many are produced in quantities of over 1 million pounds per year. Numerous chemicals are detected in the blood and urine of nearly…
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Medicine & Health Machine Learning in Health and Biomedicine
Modern statistical modeling techniques—often called machine learning—are posited as a transformative force for human health. High-profile reports of diagnostic success demonstrate…
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Medicine & Health WHO Estimates of the Global Burden of Foodborne Diseases
Illness and death from diseases caused by contaminated food are a constant threat to public health and a significant impediment to socio-economic development worldwide. To measure the global and…
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Medicine & Health DREAMS: a partnership to reduce HIV acquisition among adolescent girls and young women and generate lessons for prevention
The DREAMS Partnership is a large investment by PEPFAR and private sector partners to promote empowerment and prevent HIV acquisition through a core package of interventions for young women, their…
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Medicine & Health Voluntary Medical Male Circumcision for HIV Prevention: New Mathematical Models for Prioritizing Sub-Populations by Age & Geography
This PLOS Collection features new mathematical models that can help country decision-makers examine the potential effects of targeting sub-populations for voluntary medical male circumcision services…