The Signaling Pathways Project is a multi-omics knowledgebase based upon public, manually curated transcriptomic and cistromic (ChIP-Seq) datasets involving genetic and small molecule manipulations of…
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Medicine & Health Machine Learning in Health and BiomedicineView Collection
Modern statistical modeling techniques—often called machine learning—are posited as a transformative force for human health. High-profile reports of diagnostic success demonstrate…
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Medicine & Health WHO Estimates of the Global Burden of Foodborne DiseasesView Collection
Illness and death from diseases caused by contaminated food are a constant threat to public health and a significant impediment to socio-economic development worldwide. To measure the global and…
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Medicine & Health DREAMS: a partnership to reduce HIV acquisition among adolescent girls and young women and generate lessons for preventionView Collection
The DREAMS Partnership is a large investment by PEPFAR and private sector partners to promote empowerment and prevent HIV acquisition through a core package of interventions for young women, their…
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Medicine & Health Voluntary Medical Male Circumcision for HIV Prevention: New Mathematical Models for Prioritizing Sub-Populations by Age & GeographyView Collection
This PLOS Collection features new mathematical models that can help country decision-makers examine the potential effects of targeting sub-populations for voluntary medical male circumcision services…
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Medicine & Health Fortification AssessmentView Collection
The Fortification Assessment Coverage Toolkit (FACT) is a modular survey methodology developed by the Global Alliance for Improved Nutrition to assess population-based (i.e., staple foods and/or…
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Medicine & Health Advances in HIV Prevention, Treatment and CureView Collection
HIV infection continues to pose a critical risk to health in many countries. UNAIDS estimates that as of 2016 the total HIV-infected population was 36.7 million, including 1.8 million people newly…
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Medicine & Health Climate Change and HealthView Collection
Climate change and the impacts on health are being increasingly reported and documented. It is expected that with continued rises in global temperature and greenhouse gas emissions the effects on…
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Medicine & Health The Global Challenges of Noncommunicable DiseasesView Collection
Noncommunicable diseases (NCDs) are responsible for two-thirds of the world's deaths, one-fourth of which occur before the age of 60. Nearly 80% of NCD deaths occur in low- and middle-income…
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Medicine & Health Epidemiological metrics for the HIV epidemicView Collection
Extraordinary progress has been made to halt and reverse the spread of HIV. However, there is still a long way to go to end the epidemic, as called for in the third Sustainable Development…
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Medicine & Health Flubendazole in OnchocerciasisView Collection
Treating onchocerciasis remains a challenge as no drug effectively kills the adult worms. A new orally bioavailable formulation of flubendazole was developed and tested to find out whether it could be…