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The importance of proteostasis is becoming increasingly apparent as disrupted proteostasis and dysregulation of the proteostasis network and autophagy is associated with aging and many age-associated diseases. The papers in this Collection provide insight into the molecular and cellular machinery and mechanisms that regulate autophagy and other proteostasis pathways.
Image Credit: National Institute of Child Health and Human Development, NIH
November 12, 2019Stefanos Aivazidis, Abhilasha Jain, Abhishek K. Rauniyar, Colin C. Anderson, John O. Marentette, David J. Orlicky, Kristofer S. Fritz, Peter S. Harris, David Siegel, Kenneth N. Maclean, James R. Roede