Biology & Life Sciences

PLOS Biology Top 10%

Published November 19, 2019 Curated Collections

At PLOS Biology, we’ve always focused on publishing the highest caliber biological research. Each year, we celebrate the impact our authors have had across the biology research landscape and share out the body of work that has earned the top 10% of citations. We hope you enjoy exploring this Collection.

Image Credit: Arek Socha

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2015
2016
2017
2018

2015

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10.1371/journal.pbio.1002112

PLOS Biology Natural Selection Constrains Neutral Diversity across A Wide Range of Species
April 10, 2015 Russell B. Corbett-Detig, Daniel L. Hartl, Timothy B. Sackton
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10.1371/journal.pbio.1002036

PLOS Biology Distinct Brain Systems Mediate the Effects of Nociceptive Input and Self-Regulation on Pain
January 6, 2015 Choong-Wan Woo, Mathieu Roy, Jason T. Buhle, Tor D. Wager
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10.1371/journal.pbio.1002220

PLOS Biology Beyond the Whole-Genome Duplication: Phylogenetic Evidence for an Ancient Interspecies Hybridization in the Baker’s Yeast Lineage
August 7, 2015 Marina Marcet-Houben, Toni Gabaldón
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10.1371/journal.pbio.1002127

PLOS Biology Colour As a Signal for Entraining the Mammalian Circadian Clock
April 17, 2015 Lauren Walmsley, Lydia Hanna, Josh Mouland, Franck Martial, Alexander West, Andrew R. Smedley, David A. Bechtold, Ann R. Webb, Robert J. Lucas, Timothy M. Brown
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10.1371/journal.pbio.1002073

PLOS Biology Cortical Hierarchies Perform Bayesian Causal Inference in Multisensory Perception
February 24, 2015 Tim Rohe, Uta Noppeney
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10.1371/journal.pbio.1002328

PLOS Biology The Contribution of Network Organization and Integration to the Development of Cognitive Control
December 29, 2015 Scott Marek, Kai Hwang, William Foran, Michael N. Hallquist, Beatriz Luna
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10.1371/journal.pbio.1002309

PLOS Biology Metformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent Biosynthesis
December 1, 2015 Takla Griss, Emma E. Vincent, Robert Egnatchik, Jocelyn Chen, Eric H. Ma, Brandon Faubert, Benoit Viollet, Ralph J. DeBerardinis, Russell G. Jones
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10.1371/journal.pbio.1002251

PLOS Biology Extremely High Mutation Rate of HIV-1 In Vivo
September 16, 2015 José M. Cuevas, Ron Geller, Raquel Garijo, José López-Aldeguer, Rafael Sanjuán
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10.1371/journal.pbio.1002053

PLOS Biology FAX1, a Novel Membrane Protein Mediating Plastid Fatty Acid Export
February 3, 2015 Nannan Li, Irene Gügel, Patrick Giavalisco, Viktoria Zeisler, Lukas Schreiber, Jürgen Soll, Katrin Philippar
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10.1371/journal.pbio.1002180

PLOS Biology A Sensitive and Specific Neural Signature for Picture-Induced Negative Affect
June 22, 2015 Luke J. Chang, Peter J. Gianaros, Stephen B. Manuck, Anjali Krishnan, Tor D. Wager
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10.1371/journal.pbio.1002132

PLOS Biology Targeting the Cell Stress Response of Plasmodium falciparum to Overcome Artemisinin Resistance
April 22, 2015 Con Dogovski, Stanley Xie, Gaetan Burgio, Jess Bridgford, Sachel Mok, James McCaw, Kesinee Chotivanich, Shannon Kenny, Nina Gnädig, Judith Straimer, Zbynek Bozdech, David Fidock, Julie Simpson, Arjen Dondorp, Simon Foote, Nectarios Klonis, Leann Tilley
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10.1371/journal.pbio.1002143

PLOS Biology Restoring the ON Switch in Blind Retinas: Opto-mGluR6, a Next-Generation, Cell-Tailored Optogenetic Tool
May 7, 2015 Michiel van Wyk, Justyna Pielecka-Fortuna, Siegrid Löwel, Sonja Kleinlogel
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10.1371/journal.pbio.1002191

PLOS Biology Biofilm Formation As a Response to Ecological Competition
July 7, 2015 Nuno M. Oliveira, Esteban Martinez-Garcia, Joao Xavier, William M. Durham, Roberto Kolter, Wook Kim, Kevin R. Foster
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10.1371/journal.pbio.1002125

PLOS Biology Dynamic Endothelial Cell Rearrangements Drive Developmental Vessel Regression
April 17, 2015 Claudio A. Franco, Martin L. Jones, Miguel O. Bernabeu, Ilse Geudens, Thomas Mathivet, Andre Rosa, Felicia M. Lopes, Aida P. Lima, Anan Ragab, Russell T. Collins, Li-Kun Phng, Peter V. Coveney, Holger Gerhardt
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10.1371/journal.pbio.1002078

PLOS Biology Numerous Transitions of Sex Chromosomes in Diptera
April 16, 2015 Beatriz Vicoso, Doris Bachtrog
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10.1371/journal.pbio.1002210

PLOS Biology The Discovery, Distribution, and Evolution of Viruses Associated with Drosophila melanogaster
July 14, 2015 Claire L. Webster, Fergal M. Waldron, Shaun Robertson, Daisy Crowson, Giada Ferrari, Juan F. Quintana, Jean-Michel Brouqui, Elizabeth H. Bayne, Ben Longdon, Amy H. Buck, Brian P. Lazzaro, Jewelna Akorli, Penelope R. Haddrill, Darren J. Obbard
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10.1371/journal.pbio.1002202

PLOS Biology Lactate Regulates Metabolic and Pro-inflammatory Circuits in Control of T Cell Migration and Effector Functions
July 16, 2015 Robert Haas, Joanne Smith, Vidalba Rocher-Ros, Suchita Nadkarni, Trinidad Montero-Melendez, Fulvio D’Acquisto, Elliot J. Bland, Michele Bombardieri, Costantino Pitzalis, Mauro Perretti, Federica M. Marelli-Berg, Claudio Mauro
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10.1371/journal.pbio.1002224

PLOS Biology The Dynamics of Incomplete Lineage Sorting across the Ancient Adaptive Radiation of Neoavian Birds
August 18, 2015 Alexander Suh, Linnéa Smeds, Hans Ellegren
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10.1371/journal.pbio.1002198

PLOS Biology Imperfect Vaccination Can Enhance the Transmission of Highly Virulent Pathogens
July 25, 2015 Andrew F. Read, Susan J. Baigent, Claire Powers, Lydia B. Kgosana, Luke Blackwell, Lorraine P. Smith, David A. Kennedy, Stephen W. Walkden-Brown, Venugopal K. Nair

2016

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10.1371/journal.pbio.2001104

PLOS Biology Climate-Related Local Extinctions Are Already Widespread among Plant and Animal Species
December 8, 2016 John J. Wiens
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10.1371/journal.pbio.1002392

PLOS Biology Growth-Blocking Peptides As Nutrition-Sensitive Signals for Insulin Secretion and Body Size Regulation
February 29, 2016 Takashi Koyama, Christen K. Mirth
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10.1371/journal.pbio.1002469

PLOS Biology Distinct Global Brain Dynamics and Spatiotemporal Organization of the Salience Network
June 7, 2016 Tianwen Chen, Weidong Cai, Srikanth Ryali, Kaustubh Supekar, Vinod Menon
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10.1371/journal.pbio.2000640

PLOS Biology Cell Fate Decision as High-Dimensional Critical State Transition
December 27, 2016 Mitra Mojtahedi, Alexander Skupin, Joseph Zhou, Ivan G. Castaño, Rebecca Y. Y. Leong-Quong, Hannah Chang, Kalliopi Trachana, Alessandro Giuliani, Sui Huang
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10.1371/journal.pbio.1002517

PLOS Biology Host Gut Motility Promotes Competitive Exclusion within a Model Intestinal Microbiota
July 26, 2016 Travis J Wiles, Matthew Jemielita, Ryan P Baker, Brandon H Schlomann, Savannah L Logan, Julia Ganz, Ellie Melancon, Judith S Eisen, Karen Guillemin, Raghuveer Parthasarathy
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10.1371/journal.pbio.1002344

PLOS Biology A Novel Platform for the Potentiation of Therapeutic Antibodies Based on Antigen-Dependent Formation of IgG Hexamers at the Cell Surface
January 6, 2016 Rob N. de Jong, Frank J. Beurskens, Sandra Verploegen, Kristin Strumane, Muriel D. van Kampen, Marleen Voorhorst, Wendy Horstman, Patrick J. Engelberts, Simone C. Oostindie, Guanbo Wang, Albert J. R. Heck, Janine Schuurman, Paul W. H. I. Parren
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10.1371/journal.pbio.1002336

PLOS Biology Exosomes Mediate LTB₄ Release during Neutrophil Chemotaxis
January 7, 2016 Ritankar Majumdar, Aidin Tavakoli Tameh, Carole A. Parent
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10.1371/journal.pbio.1002585

PLOS Biology Single-Cell-Based Analysis Highlights a Surge in Cell-to-Cell Molecular Variability Preceding Irreversible Commitment in a Differentiation Process
December 27, 2016 Angélique Richard, Loïs Boullu, Ulysse Herbach, Arnaud Bonnafoux, Valérie Morin, Elodie Vallin, Anissa Guillemin, Nan Papili Gao, Rudiyanto Gunawan, Jérémie Cosette, Ophélie Arnaud, Jean-Jacques Kupiec, Thibault Espinasse, Sandrine Gonin-Giraud, Olivier Gandrillon
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10.1371/journal.pbio.1002394

PLOS Biology Horizontal DNA Transfer Mechanisms of Bacteria as Weapons of Intragenomic Conflict
March 2, 2016 Nicholas J. Croucher, Rafal Mostowy, Christopher Wymant, Paul Turner, Stephen D. Bentley, Christophe Fraser
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10.1371/journal.pbio.1002456

PLOS Biology Badges to Acknowledge Open Practices: A Simple, Low-Cost, Effective Method for Increasing Transparency
May 12, 2016 Mallory C. Kidwell, Ljiljana B. Lazarević, Erica Baranski, Tom E. Hardwicke, Sarah Piechowski, Lina-Sophia Falkenberg, Curtis Kennett, Agnieszka Slowik, Carina Sonnleitner, Chelsey Hess-Holden, Timothy M. Errington, Susann Fiedler, Brian A. Nosek
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10.1371/journal.pbio.1002379

PLOS Biology Phylogenomics Reveals Three Sources of Adaptive Variation during a Rapid Radiation
February 12, 2016 James B. Pease, David C. Haak, Matthew W. Hahn, Leonie C. Moyle
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10.1371/journal.pbio.1002564

PLOS Biology Associative Mechanisms Allow for Social Learning and Cultural Transmission of String Pulling in an Insect
October 4, 2016 Sylvain Alem, Clint J. Perry, Xingfu Zhu, Olli J. Loukola, Thomas Ingraham, Eirik Søvik, Lars Chittka
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10.1371/journal.pbio.1002352

PLOS Biology Microbial Hub Taxa Link Host and Abiotic Factors to Plant Microbiome Variation
January 20, 2016 Matthew T. Agler, Jonas Ruhe, Samuel Kroll, Constanze Morhenn, Sang-Tae Kim, Detlef Weigel, Eric M. Kemen
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10.1371/journal.pbio.1002333

PLOS Biology Reproducible Research Practices and Transparency across the Biomedical Literature
January 4, 2016 Shareen A. Iqbal, Joshua D. Wallach, Muin J. Khoury, Sheri D. Schully, John P. A. Ioannidis
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10.1371/journal.pbio.2000016

PLOS Biology Regulation of the Human Telomerase Gene TERT by Telomere Position Effect—Over Long Distances (TPE-OLD): Implications for Aging and Cancer
December 15, 2016 Wanil Kim, Andrew T. Ludlow, Jaewon Min, Jerome D. Robin, Guido Stadler, Ilgen Mender, Tsung-Po Lai, Ning Zhang, Woodring E. Wright, Jerry W. Shay
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10.1371/journal.pbio.1002454

PLOS Biology Ionotropic Chemosensory Receptors Mediate the Taste and Smell of Polyamines
May 4, 2016 Ashiq Hussain, Mo Zhang, Habibe K. Üçpunar, Thomas Svensson, Elsa Quillery, Nicolas Gompel, Rickard Ignell, Ilona C. Grunwald Kadow
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10.1371/journal.pbio.1002541

PLOS Biology Relative Citation Ratio (RCR): A New Metric That Uses Citation Rates to Measure Influence at the Article Level
September 6, 2016 B. Ian Hutchins, Xin Yuan, James M. Anderson, George M. Santangelo
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10.1371/journal.pbio.1002338

PLOS Biology ALS-Causing Mutations Significantly Perturb the Self-Assembly and Interaction with Nucleic Acid of the Intrinsically Disordered Prion-Like Domain of TDP-43
January 6, 2016 Liangzhong Lim, Yuanyuan Wei, Yimei Lu, Jianxing Song
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10.1371/journal.pbio.2000234

PLOS Biology Shedding Light on the Grey Zone of Speciation along a Continuum of Genomic Divergence
December 27, 2016 Camille Roux, Christelle Fraïsse, Jonathan Romiguier, Yoann Anciaux, Nicolas Galtier, Nicolas Bierne
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10.1371/journal.pbio.1002353

PLOS Biology Evolutionary Novelty in a Butterfly Wing Pattern through Enhancer Shuffling
January 15, 2016 Richard W. R. Wallbank, Simon W. Baxter, Carolina Pardo-Diaz, Joseph J. Hanly, Simon H. Martin, James Mallet, Kanchon K. Dasmahapatra, Camilo Salazar, Mathieu Joron, Nicola Nadeau, W. Owen McMillan, Chris D. Jiggins
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10.1371/journal.pbio.1002357

PLOS Biology Standardized Assessment of Biodiversity Trends in Tropical Forest Protected Areas: The End Is Not in Sight
January 19, 2016 Lydia Beaudrot, Jorge A. Ahumada, Timothy O'Brien, Patricia Alvarez-Loayza, Kelly Boekee, Ahimsa Campos-Arceiz, David Eichberg, Santiago Espinosa, Eric Fegraus, Christine Fletcher, Krisna Gajapersad, Chris Hallam, Johanna Hurtado, Patrick A. Jansen, Amit Kumar, Eileen Larney, Marcela Guimarães Moreira Lima, Colin Mahony, Emanuel H. Martin, Alex McWilliam, Badru Mugerwa, Mireille Ndoundou-Hockemba, Jean Claude Razafimahaimodison, Hugo Romero-Saltos, Francesco Rovero, Julia Salvador, Fernanda Santos, Douglas Sheil, Wilson R. Spironello, Michael R. Willig, Nurul L. Winarni, Alex Zvoleff, Sandy J. Andelman
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10.1371/journal.pbio.2000225

PLOS Biology Phylosymbiosis: Relationships and Functional Effects of Microbial Communities across Host Evolutionary History
November 18, 2016 Andrew W. Brooks, Kevin D. Kohl, Robert M. Brucker, Edward J. van Opstal, Seth R. Bordenstein
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10.1371/journal.pbio.1002415

PLOS Biology Remotely Sensed High-Resolution Global Cloud Dynamics for Predicting Ecosystem and Biodiversity Distributions
March 31, 2016 Adam M. Wilson, Walter Jetz
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10.1371/journal.pbio.1002466

PLOS Biology Neuronal Hyperactivity Disturbs ATP Microgradients, Impairs Microglial Motility, and Reduces Phagocytic Receptor Expression Triggering Apoptosis/Microglial Phagocytosis Uncoupling
May 26, 2016 Oihane Abiega, Sol Beccari, Irune Diaz-Aparicio, Agnes Nadjar, Sophie Layé, Quentin Leyrolle, Diego Gómez-Nicola, María Domercq, Alberto Pérez-Samartín, Víctor Sánchez-Zafra, Iñaki Paris, Jorge Valero, Julie C. Savage, Chin-Wai Hui, Marie-Ève Tremblay, Juan J. P. Deudero, Amy L. Brewster, Anne E. Anderson, Laura Zaldumbide, Lara Galbarriatu, Ainhoa Marinas, Maria dM. Vivanco, Carlos Matute, Mirjana Maletic-Savatic, Juan M. Encinas, Amanda Sierra

2017

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10.1371/journal.pbio.2002183

PLOS Biology RNA stores tau reversibly in complex coacervates
July 6, 2017 Xuemei Zhang, Yanxian Lin, Neil A. Eschmann, Hongjun Zhou, Jennifer N. Rauch, Israel Hernandez, Elmer Guzman, Kenneth S. Kosik, Songi Han
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10.1371/journal.pbio.2001272

PLOS Biology ARGONAUTE10 promotes the degradation of miR165/6 through the SDN1 and SDN2 exonucleases in Arabidopsis
February 23, 2017 Yu Yu, Lijuan Ji, Brandon H. Le, Jixian Zhai, Jiayi Chen, Elizabeth Luscher, Lei Gao, Chunyan Liu, Xiaofeng Cao, Beixin Mo, Jinbiao Ma, Blake C. Meyers, Xuemei Chen
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10.1371/journal.pbio.1002598

PLOS Biology Neurocomputational mechanisms underlying subjective valuation of effort costs
February 24, 2017 Trevor T.-J. Chong, Matthew Apps, Kathrin Giehl, Annie Sillence, Laura L. Grima, Masud Husain
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10.1371/journal.pbio.2000735

PLOS Biology Three-dimensional preservation of cellular and subcellular structures suggests 1.6 billion-year-old crown-group red algae
March 14, 2017 Stefan Bengtson, Therese Sallstedt, Veneta Belivanova, Martin Whitehouse
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10.1371/journal.pbio.2003467

PLOS Biology Disentangling metabolic functions of bacteria in the honey bee gut
December 12, 2017 Lucie Kešnerová, Ruben A. T. Mars, Kirsten M. Ellegaard, Michaël Troilo, Uwe Sauer, Philipp Engel
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10.1371/journal.pbio.2001894

PLOS Biology Local introduction and heterogeneous spatial spread of dengue-suppressing Wolbachia through an urban population of Aedes aegypti
May 30, 2017 Tom L. Schmidt, Nicholas H. Barton, Gordana Rašić, Andrew P. Turley, Brian L. Montgomery, Inaki Iturbe-Ormaetxe, Peter E. Cook, Peter A. Ryan, Scott A. Ritchie, Ary A. Hoffmann, Scott L. O’Neill, Michael Turelli
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10.1371/journal.pbio.2001402

PLOS Biology Digital Health: Tracking Physiomes and Activity Using Wearable Biosensors Reveals Useful Health-Related Information
January 12, 2017 Xiao Li, Jessilyn Dunn, Denis Salins, Gao Zhou, Wenyu Zhou, Sophia Miryam Schüssler-Fiorenza Rose, Dalia Perelman, Elizabeth Colbert, Ryan Runge, Shannon Rego, Ria Sonecha, Somalee Datta, Tracey McLaughlin, Michael P. Snyder
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10.1371/journal.pbio.2004086

PLOS Biology Fundamental properties of the mammalian innate immune system revealed by multispecies comparison of type I interferon responses
December 18, 2017 Andrew E. Shaw, Joseph Hughes, Quan Gu, Abdelkader Behdenna, Joshua B. Singer, Tristan Dennis, Richard J. Orton, Mariana Varela, Robert J. Gifford, Sam J. Wilson, Massimo Palmarini
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10.1371/journal.pbio.2001573

PLOS Biology Molecular regionalization of the developing amphioxus neural tube challenges major partitions of the vertebrate brain
April 19, 2017 Beatriz Albuixech-Crespo, Laura López-Blanch, Demian Burguera, Ignacio Maeso, Luisa Sánchez-Arrones, Juan Antonio Moreno-Bravo, Ildiko Somorjai, Juan Pascual-Anaya, Eduardo Puelles, Paola Bovolenta, Jordi Garcia-Fernàndez, Luis Puelles, Manuel Irimia, José Luis Ferran
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10.1371/journal.pbio.2001930

PLOS Biology MAIT cells launch a rapid, robust and distinct hyperinflammatory response to bacterial superantigens and quickly acquire an anergic phenotype that impedes their cognate antimicrobial function: Defining a novel mechanism of superantigen-induced immunopathology and immunosuppression
June 20, 2017 Christopher R. Shaler, Joshua Choi, Patrick T. Rudak, Arash Memarnejadian, Peter A. Szabo, Mauro E. Tun-Abraham, Jamie Rossjohn, Alexandra J. Corbett, James McCluskey, John K. McCormick, Olivier Lantz, Roberto Hernandez-Alejandro, S.M. Mansour Haeryfar
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Flickr user josefstuefer

PLOS Biology ‘Spin’ in published biomedical literature: A methodological systematic review
September 11, 2017 Kellia Chiu, Quinn Grundy, Lisa Bero
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10.1371/journal.pbio.2001861

PLOS Biology Antibiotic exposure perturbs the gut microbiota and elevates mortality in honeybees
March 14, 2017 Kasie Raymann, Zack Shaffer, Nancy A. Moran
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10.1371/journal.pbio.2002214

PLOS Biology The in vivo structure of biological membranes and evidence for lipid domains
May 23, 2017 Jonathan D. Nickels, Sneha Chatterjee, Christopher B. Stanley, Shuo Qian, Xiaolin Cheng, Dean A. A. Myles, Robert F. Standaert, James G. Elkins, John Katsaras
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10.1371/journal.pbio.2003790

PLOS Biology The sea cucumber genome provides insights into morphological evolution and visceral regeneration
October 12, 2017 Xiaojun Zhang, Lina Sun, Jianbo Yuan, Yamin Sun, Yi Gao, Libin Zhang, Shihao Li, Hui Dai, Jean-François Hamel, Chengzhang Liu, Yang Yu, Shilin Liu, Wenchao Lin, Kaimin Guo, Songjun Jin, Peng Xu, Kenneth B. Storey, Pin Huan, Tao Zhang, Yi Zhou, Jiquan Zhang, Chenggang Lin, Xiaoni Li, Lili Xing, Da Huo, Mingzhe Sun, Lei Wang, Annie Mercier, Fuhua Li, Hongsheng Yang, Jianhai Xiang
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10.1371/journal.pbio.2001882

PLOS Biology Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain
March 21, 2017 Nathanael G. Lintner, Kim F. McClure, Donna Petersen, Allyn T. Londregan, David W. Piotrowski, Liuqing Wei, Jun Xiao, Michael Bolt, Paula M. Loria, Bruce Maguire, Kieran F. Geoghegan, Austin Huang, Tim Rolph, Spiros Liras, Jennifer A. Doudna, Robert G. Dullea, Jamie H. D. Cate
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10.1371/journal.pbio.2000374

PLOS Biology The mechanism of sirtuin 2–mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease
March 3, 2017 Rita Machado de Oliveira, Hugo Vicente Miranda, Laetitia Francelle, Raquel Pinho, Éva M. Szegö, Renato Martinho, Francesca Munari, Diana F. Lázaro, Sébastien Moniot, Patrícia Guerreiro, Luis Fonseca, Zrinka Marijanovic, Pedro Antas, Ellen Gerhardt, Francisco Javier Enguita, Bruno Fauvet, Deborah Penque, Teresa Faria Pais, Qiang Tong, Stefan Becker, Sebastian Kügler, Hilal Ahmed Lashuel, Clemens Steegborn, Markus Zweckstetter, Tiago Fleming Outeiro
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Yoshida et al. / pbio.2002266

PLOS Biology Comparative genomics of the tardigrades Hypsibius dujardini and Ramazzottius varieornatus
July 27, 2017 Yuki Yoshida, Georgios Koutsovoulos, Dominik R. Laetsch, Lewis Stevens, Sujai Kumar, Daiki D. Horikawa, Kyoko Ishino, Shiori Komine, Takekazu Kunieda, Masaru Tomita, Mark Blaxter, Kazuharu Arakawa
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10.1371/journal.pbio.2000797

PLOS Biology Empirical assessment of published effect sizes and power in the recent cognitive neuroscience and psychology literature
March 2, 2017 Denes Szucs, John P. A. Ioannidis
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10.1371/journal.pbio.2000644

PLOS Biology Phenotypic heterogeneity promotes adaptive evolution
May 9, 2017 Zoltán Bódi, Zoltán Farkas, Dmitry Nevozhay, Dorottya Kalapis, Viktória Lázár, Bálint Csörgő, Ákos Nyerges, Béla Szamecz, Gergely Fekete, Balázs Papp, Hugo Araújo, José L. Oliveira, Gabriela Moura, Manuel A. S. Santos, Tamás Székely Jr, Gábor Balázsi, Csaba Pál
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10.1371/journal.pbio.2000862

PLOS Biology Commensal bacteria and essential amino acids control food choice behavior and reproduction
April 25, 2017 Ricardo Leitão-Gonçalves, Zita Carvalho-Santos, Ana Patrícia Francisco, Gabriela Tondolo Fioreze, Margarida Anjos, Célia Baltazar, Ana Paula Elias, Pavel M. Itskov, Matthew D. W. Piper, Carlos Ribeiro
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10.1371/journal.pbio.2000689

PLOS Biology The enteric nervous system promotes intestinal health by constraining microbiota composition
February 16, 2017 Annah S. Rolig, Erika K. Mittge, Julia Ganz, Josh V. Troll, Ellie Melancon, Travis J. Wiles, Kristin Alligood, W. Zac Stephens, Judith S. Eisen, Karen Guillemin

2018

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10.1371/journal.pbio.2004559

PLOS Biology Parallel trends in cortical gray and white matter architecture and connections in primates allow fine study of pathways in humans and reveal network disruptions in autism
February 5, 2018 Basilis Zikopoulos, Miguel Ángel García-Cabezas, Helen Barbas
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10.1371/journal.pbio.2004880

PLOS Biology METTL3-mediated m⁶A modification is required for cerebellar development
June 7, 2018 Chen-Xin Wang, Guan-Shen Cui, Xiuying Liu, Kai Xu, Meng Wang, Xin-Xin Zhang, Li-Yuan Jiang, Ang Li, Ying Yang, Wei-Yi Lai, Bao-Fa Sun, Gui-Bin Jiang, Hai-Lin Wang, Wei-Min Tong, Wei Li, Xiu-Jie Wang, Yun-Gui Yang, Qi Zhou
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10.1371/journal.pbio.2004122

PLOS Biology Active photosynthetic inhibition mediated by MPK3/MPK6 is critical to effector-triggered immunity
May 3, 2018 Jianbin Su, Liuyi Yang, Qiankun Zhu, Hongjiao Wu, Yi He, Yidong Liu, Juan Xu, Dean Jiang, Shuqun Zhang
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10.1371/journal.pbio.2004399

PLOS Biology Activation of temperature-sensitive TRPV1-like receptors in ARC POMC neurons reduces food intake
April 24, 2018 Jae Hoon Jeong, Dong Kun Lee, Shun-Mei Liu, Streamson C. Chua Jr., Gary J. Schwartz, Young-Hwan Jo
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10.1371/journal.pbio.2003174

PLOS Biology A damped oscillator imposes temporal order on posterior gap gene expression in Drosophila
February 16, 2018 Berta Verd, Erik Clark, Karl R. Wotton, Hilde Janssens, Eva Jiménez-Guri, Anton Crombach, Johannes Jaeger
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10.1371/journal.pbio.2003703

PLOS Biology Population genomics of Mesolithic Scandinavia: Investigating early postglacial migration routes and high-latitude adaptation
January 9, 2018 Torsten Günther, Helena Malmström, Emma M. Svensson, Ayça Omrak, Federico Sánchez-Quinto, Gülşah M. Kılınç, Maja Krzewińska, Gunilla Eriksson, Magdalena Fraser, Hanna Edlund, Arielle R. Munters, Alexandra Coutinho, Luciana G. Simões, Mário Vicente, Anders Sjölander, Berit Jansen Sellevold, Roger Jørgensen, Peter Claes, Mark D. Shriver, Cristina Valdiosera, Mihai G. Netea, Jan Apel, Kerstin Lidén, Birgitte Skar, Jan Storå, Anders Götherström, Mattias Jakobsson
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10.1371/journal.pbio.2006643

PLOS Biology Large-scale investigation of the reasons why potentially important genes are ignored
September 18, 2018 Thomas Stoeger, Martin Gerlach, Richard I. Morimoto, Luís A. Nunes Amaral
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10.1371/journal.pbio.2002399

PLOS Biology Hippo signaling controls cell cycle and restricts cell plasticity in planarians
January 22, 2018 Nídia de Sousa, Gustavo Rodríguez-Esteban, Jose Ignacio Rojo-Laguna, Emili Saló, Teresa Adell
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10.1371/journal.pbio.2003862

PLOS Biology Compositional shifts in root-associated bacterial and archaeal microbiota track the plant life cycle in field-grown rice
February 23, 2018 Joseph A. Edwards, Christian M. Santos-Medellín, Zachary S. Liechty, Bao Nguyen, Eugene Lurie, Shane Eason, Gregory Phillips, Venkatesan Sundaresan
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nosheep, Pixabay

PLOS Biology Preclinical efficacy studies in investigator brochures: Do they enable risk–benefit assessment?
April 5, 2018 Susanne Wieschowski, William Wei Lim Chin, Carole Federico, Sören Sievers, Jonathan Kimmelman, Daniel Strech
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10.1371/journal.pbio.2004845

PLOS Biology Treadmilling analysis reveals new insights into dynamic FtsZ ring architecture
May 18, 2018 Diego A. Ramirez-Diaz, Daniela A. García-Soriano, Ana Raso, Jonas Mücksch, Mario Feingold, Germán Rivas, Petra Schwille
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10.1371/journal.pbio.2001959

PLOS Biology Inflammation arising from obesity reduces taste bud abundance and inhibits renewal
March 20, 2018 Andrew Kaufman, Ezen Choo, Anna Koh, Robin Dando
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10.1371/journal.pbio.2004830

PLOS Biology Comparative genomics of bdelloid rotifers: Insights from desiccating and nondesiccating species
April 24, 2018 Reuben W. Nowell, Pedro Almeida, Christopher G. Wilson, Thomas P. Smith, Diego Fontaneto, Alastair Crisp, Gos Micklem, Alan Tunnacliffe, Chiara Boschetti, Timothy G. Barraclough
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10.1371/journal.pbio.2005853

PLOS Biology Mice learn to avoid regret
June 21, 2018 Brian M. Sweis, Mark J. Thomas, A. David Redish
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10.1371/journal.pbio.2005687

PLOS Biology Rif1 prolongs the embryonic S phase at the Drosophila mid-blastula transition
May 10, 2018 Charles A. Seller, Patrick H. O’Farrell
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10.1371/journal.pbio.2004411

PLOS Biology Role of the AP-5 adaptor protein complex in late endosome-to-Golgi retrieval
January 30, 2018 Jennifer Hirst, Daniel N. Itzhak, Robin Antrobus, Georg H. H. Borner, Margaret S. Robinson
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10.1371/journal.pbio.2003904

PLOS Biology Evaluation of e-liquid toxicity using an open-source high-throughput screening assay
March 27, 2018 M. Flori Sassano, Eric S. Davis, James E. Keating, Bryan T. Zorn, Tavleen K. Kochar, Matthew C. Wolfgang, Gary L. Glish, Robert Tarran
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10.1371/journal.pbio.2004328

PLOS Biology The Plasmodium falciparum transcriptome in severe malaria reveals altered expression of genes involved in important processes including surface antigen–encoding var genes
March 12, 2018 Gerry Q. Tonkin-Hill, Leily Trianty, Rintis Noviyanti, Hanh H. T. Nguyen, Boni F. Sebayang, Daniel A. Lampah, Jutta Marfurt, Simon A. Cobbold, Janavi S. Rambhatla, Malcolm J. McConville, Stephen J. Rogerson, Graham V. Brown, Karen P. Day, Ric N. Price, Nicholas M. Anstey, Anthony T. Papenfuss, Michael F. Duffy
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PLOS Biology Drosophila melanogaster establishes a species-specific mutualistic interaction with stable gut-colonizing bacteria
July 5, 2018 Inês S. Pais, Rita S. Valente, Marta Sporniak, Luis Teixeira
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PLOS Biology Classes and continua of hippocampal CA1 inhibitory neurons revealed by single-cell transcriptomics
June 18, 2018 Kenneth D. Harris, Hannah Hochgerner, Nathan G. Skene, Lorenza Magno, Linda Katona, Carolina Bengtsson Gonzales, Peter Somogyi, Nicoletta Kessaris, Sten Linnarsson, Jens Hjerling-Leffler
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PLOS Biology Nitric oxide-mediated posttranslational modifications control neurotransmitter release by modulating complexin farnesylation and enhancing its clamping ability
April 9, 2018 Susan W. Robinson, Julie-Myrtille Bourgognon, Jereme G. Spiers, Carlo Breda, Susanna Campesan, Adrian Butcher, Giovanna R. Mallucci, David Dinsdale, Nobuhiro Morone, Raj Mistry, Tim M. Smith, Maria Guerra-Martin, R. A. John Challiss, Flaviano Giorgini, Joern R. Steinert
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PLOS Biology Neutrophils kill the parasite Trichomonas vaginalis using trogocytosis
February 6, 2018 Frances Mercer, Shek Hang Ng, Taylor M. Brown, Grace Boatman, Patricia J. Johnson
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PLOS Biology Is the sky the limit? On the expansion threshold of a species’ range
June 15, 2018 Jitka Polechová
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PLOS Biology Climate change could drive marine food web collapse through altered trophic flows and cyanobacterial proliferation
January 9, 2018 Hadayet Ullah, Ivan Nagelkerken, Silvan U. Goldenberg, Damien A. Fordham
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PLOS Biology Metallochaperone UreG serves as a new target for design of urease inhibitor: A novel strategy for development of antimicrobials
January 10, 2018 Xinming Yang, Mohamad Koohi-Moghadam, Runming Wang, Yuen-Yan Chang, Patrick C. Y. Woo, Junwen Wang, Hongyan Li, Hongzhe Sun
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PLOS Biology The emergence of the visual word form: Longitudinal evolution of category-specific ventral visual areas during reading acquisition
March 6, 2018 Ghislaine Dehaene-Lambertz, Karla Monzalvo, Stanislas Dehaene
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10.1371/journal.pbio.2003962

PLOS Biology Design of synthetic bacterial communities for predictable plant phenotypes
February 20, 2018 Sur Herrera Paredes, Tianxiang Gao, Theresa F. Law, Omri M. Finkel, Tatiana Mucyn, Paulo José Pereira Lima Teixeira, Isaí Salas González, Meghan E. Feltcher, Matthew J. Powers, Elizabeth A. Shank, Corbin D. Jones, Vladimir Jojic, Jeffery L. Dangl, Gabriel Castrillo
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10.1371/journal.pbio.2003892

PLOS Biology Identification of osmoadaptive strategies in the halophile, heterotrophic ciliate Schmidingerothrix salinarum
January 22, 2018 Lea Weinisch, Steffen Kühner, Robin Roth, Maria Grimm, Tamara Roth, Daili J. A. Netz, Antonio J. Pierik, Sabine Filker
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PLOS Biology Cell signaling heterogeneity is modulated by both cell-intrinsic and -extrinsic mechanisms: An integrated approach to understanding targeted therapy
March 9, 2018 Eunjung Kim, Jae-Young Kim, Matthew A. Smith, Eric B. Haura, Alexander R. A. Anderson
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10.1371/journal.pbio.2005594

PLOS Biology The mammalian decidual cell evolved from a cellular stress response
August 24, 2018 Eric M. Erkenbrack, Jamie D. Maziarz, Oliver W. Griffith, Cong Liang, Arun R. Chavan, Mauris C. Nnamani, Günter P. Wagner
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10.1371/journal.pbio.2003698

PLOS Biology Anteroposterior axis patterning by early canonical Wnt signaling during hemichordate development
January 16, 2018 Sébastien Darras, Jens H. Fritzenwanker, Kevin R. Uhlinger, Ellyn Farrelly, Ariel M. Pani, Imogen A. Hurley, Rachael P. Norris, Michelle Osovitz, Mark Terasaki, Mike Wu, Jochanan Aronowicz, Marc Kirschner, John C. Gerhart, Christopher J. Lowe
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PLOS Biology Reproducibility of preclinical animal research improves with heterogeneity of study samples
February 22, 2018 Bernhard Voelkl, Lucile Vogt, Emily S. Sena, Hanno Würbel
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10.1371/journal.pbio.2005970

PLOS Biology CellProfiler 3.0: Next-generation image processing for biology
July 3, 2018 Claire McQuin, Allen Goodman, Vasiliy Chernyshev, Lee Kamentsky, Beth A. Cimini, Kyle W. Karhohs, Minh Doan, Liya Ding, Susanne M. Rafelski, Derek Thirstrup, Winfried Wiegraebe, Shantanu Singh, Tim Becker, Juan C. Caicedo, Anne E. Carpenter
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PLOS Biology Peripherally derived macrophages modulate microglial function to reduce inflammation after CNS injury
October 17, 2018 Andrew D. Greenhalgh, Juan G. Zarruk, Luke M. Healy, Sam J. Baskar Jesudasan, Priya Jhelum, Christopher K. Salmon, Albert Formanek, Matthew V. Russo, Jack P. Antel, Dorian B. McGavern, Barry W. McColl, Samuel David
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PLOS Biology Serial representation of items during working memory maintenance at letter-selective cortical sites
August 15, 2018 Ali Bahramisharif, Ole Jensen, Joshua Jacobs, John Lisman
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10.1371/journal.pbio.2003864

PLOS Biology Endoplasmic reticulum-plasma membrane contact sites integrate sterol and phospholipid regulation
May 21, 2018 Evan Quon, Yves Y. Sere, Neha Chauhan, Jesper Johansen, David P. Sullivan, Jeremy S. Dittman, William J. Rice, Robin B. Chan, Gilbert Di Paolo, Christopher T. Beh, Anant K. Menon
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PLOS Biology Control of recollection by slow gamma dominating mid-frequency gamma in hippocampus CA1
January 18, 2018 Dino Dvorak, Basma Radwan, Fraser T. Sparks, Zoe Nicole Talbot, André A. Fenton
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PLOS Biology Glucotypes reveal new patterns of glucose dysregulation
July 24, 2018 Heather Hall, Dalia Perelman, Alessandra Breschi, Patricia Limcaoco, Ryan Kellogg, Tracey McLaughlin, Michael Snyder
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10.1371/journal.pbio.2006352

PLOS Biology Nitrogen fixation in a landrace of maize is supported by a mucilage-associated diazotrophic microbiota
August 7, 2018 Allen Van Deynze, Pablo Zamora, Pierre-Marc Delaux, Cristobal Heitmann, Dhileepkumar Jayaraman, Shanmugam Rajasekar, Danielle Graham, Junko Maeda, Donald Gibson, Kevin D. Schwartz, Alison M. Berry, Srijak Bhatnagar, Guillaume Jospin, Aaron Darling, Richard Jeannotte, Javier Lopez, Bart C. Weimer, Jonathan A. Eisen, Howard-Yana Shapiro, Jean-Michel Ané, Alan B. Bennett

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