Medicine & Health

Immunodeficiency

Published October 17, 2016 Curated Collections

The Clinical Immunology Collection has been organized into broad categories in response to the commonly articulated request from our users that we provide more structured and efficient access to papers of interest in the PLOS corpus. This section includes papers about immunodeficiency.

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Research Articles

Research Articles

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10.1371/journal.ppat.1005072

PLOS Pathogens Arming of MAIT Cell Cytolytic Antimicrobial Activity Is Induced by IL-7 and Defective in HIV-1 Infection
August 21, 2015 Edwin Leeansyah, Jenny Svärd, Joana Dias, Marcus Buggert, Jessica Nyström, Máire F. Quigley, Markus Moll, Anders Sönnerborg, Piotr Nowak, Johan K. Sandberg
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10.1371/journal.ppat.1005270

PLOS Pathogens PD-L1 Blockade Differentially Impacts Regulatory T Cells from HIV-Infected Individuals Depending on Plasma Viremia
December 3, 2015 Cristina Peligero, Jordi Argilaguet, Roberto Güerri-Fernandez, Berta Torres, Carmen Ligero, Pilar Colomer, Montserrat Plana, Hernando Knobel, Felipe García, Andreas Meyerhans
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10.1371/journal.ppat.1005287

PLOS Pathogens Early Loss of Splenic Tfh Cells in SIV-Infected Rhesus Macaques
December 7, 2015 Félicien Moukambi, Henintsoa Rabezanahary, Vasco Rodrigues, Gina Racine, Lynda Robitaille, Bernard Krust, Guadalupe Andreani, Calayselvy Soundaramourty, Ricardo Silvestre, Mireille Laforge, Jérôme Estaquier
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10.1371/journal.ppat.1005349

PLOS Pathogens TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection
January 7, 2016 Glen M. Chew, Tsuyoshi Fujita, Gabriela M. Webb, Benjamin J. Burwitz, Helen L. Wu, Jason S. Reed, Katherine B. Hammond, Kiera L. Clayton, Naoto Ishii, Mohamed Abdel-Mohsen, Teri Liegler, Brooks I. Mitchell, Frederick M. Hecht, Mario Ostrowski, Cecilia M. Shikuma, Scott G. Hansen, Mark Maurer, Alan J. Korman, Steven G. Deeks, Jonah B. Sacha, Lishomwa C. Ndhlovu
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10.1371/journal.pgen.1004914

PLOS Genetics Structured Observations Reveal Slow HIV-1 CTL Escape
February 2, 2015 Hannah E. Roberts, Jacob Hurst, Nicola Robinson, Helen Brown, Peter Flanagan, Laura Vass, Sarah Fidler, Jonathan Weber, Abdel Babiker, Rodney E. Phillips, Angela R. McLean, John Frater, SPARTAC trial investigators
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10.1371/journal.pcbi.1004665

PLOS Computational Biology Modeling the Slow CD4+ T Cell Decline in HIV-Infected Individuals
December 28, 2015 Sunpeng Wang, Patricia Hottz, Mauro Schechter, Libin Rong
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10.1371/journal.pcbi.1004492

PLOS Computational Biology Broad CTL Response in Early HIV Infection Drives Multiple Concurrent CTL Escapes
October 27, 2015 Sivan Leviyang, Vitaly V. Ganusov
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10.1371/journal.pcbi.1004721

PLOS Computational Biology Investigating the Consequences of Interference between Multiple CD8⁺ T Cell Escape Mutations in Early HIV Infection
February 1, 2016 Victor Garcia, Marcus W. Feldman, Roland R. Regoes
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10.1371/journal.pone.0000992

PLOS ONE Deletion of PKBα/Akt1 Affects Thymic Development
October 3, 2007 Elisabeth Fayard, Jason Gill, Magdalena Paolino, Debby Hynx, Georg A. Holländer, Brian A. Hemmings
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10.1371/journal.pone.0004516

PLOS ONE Impaired Replication Stress Response in Cells from Immunodeficiency Patients Carrying Cernunnos/XLF Mutations
February 18, 2009 Michal Schwartz, Yifat S. Oren, Assaf C. Bester, Ayelet Rahat, Ruthy Sfez, Shlomo Yitzchaik, Jean-Pierre de Villartay, Batsheva Kerem
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10.1371/journal.pone.0005234

PLOS ONE Chronic Granulomatous Disease: The European Experience
April 21, 2009 J. Merlijn van den Berg, Elsbeth van Koppen, Anders Åhlin, Bernd H. Belohradsky, Ewa Bernatowska, Lucien Corbeel, Teresa Español, Alain Fischer, Magdalena Kurenko-Deptuch, Richard Mouy, Theoni Petropoulou, Joachim Roesler, Reinhard Seger, Marie-José Stasia, Niels H. Valerius, Ron S. Weening, Baruch Wolach, Dirk Roos, Taco W. Kuijpers
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10.1371/journal.pone.0005321

PLOS ONE Screening for C3 Deficiency in Newborns Using Microarrays
April 24, 2009 Magdalena Janzi, Ronald Sjöberg, Jinghong Wan, Björn Fischler, Ulrika von Döbeln, Lourdes Isaac, Peter Nilsson, Lennart Hammarström
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10.1371/journal.pone.0008870

PLOS ONE Generation of Knockout Rats with X-Linked Severe Combined Immunodeficiency (X-SCID) Using Zinc-Finger Nucleases
January 25, 2010 Tomoji Mashimo, Akiko Takizawa, Birger Voigt, Kazuto Yoshimi, Hiroshi Hiai, Takashi Kuramoto, Tadao Serikawa
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10.1371/journal.pone.0019464

PLOS ONE Heterochromatic Genes Undergo Epigenetic Changes and Escape Silencing in Immunodeficiency, Centromeric Instability, Facial Anomalies (ICF) Syndrome
April 29, 2011 Marie-Elisabeth BRUN, Erica LANA, Isabelle RIVALS, Gérard LEFRANC, Pierre SARDA, Mireille CLAUSTRES, André Mégarbané, Albertina De Sario
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10.1371/journal.pgen.1002476

PLOS Genetics High-Density SNP Mapping of the HLA Region Identifies Multiple Independent Susceptibility Loci Associated with Selective IgA Deficiency
January 26, 2012 Ricardo Ferreira, Qiang Pan-Hammarström, Robert Graham, Gumersindo Fontán, Annette Lee, Ward Ortmann, Ning Wang, Elena Urcelay, Miguel Fernández-Arquero, Concepción Núñez, Gudmundur Jorgensen, Björn Ludviksson, Sinikka Koskinen, Katri Haimila, Leonid Padyukov, Peter Gregersen, Lennart Hammarström, Timothy Behrens
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10.1371/journal.pone.0030494

PLOS ONE The Kinetics of Early T and B Cell Immune Recovery after Bone Marrow Transplantation in RAG-2-Deficient SCID Patients
January 25, 2012 Atar Lev, Amos Simon, Mor Bareket, Bella Bielorai, Daphna Hutt, Ninette Amariglio, Gideon Rechavi, Raz Somech
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10.1371/journal.pone.0074893

PLOS ONE Interferon Signature in the Blood in Inflammatory Common Variable Immune Deficiency
September 17, 2013 Joon Park, Indira Munagala, Hui Xu, Derek Blankenship, Patrick Maffucci, Damien Chaussabel, Jacques Banchereau, Virginia Pascual, Charlotte Cunningham-Rundles
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10.1371/journal.pone.0077204

PLOS ONE NADPH Oxidase Deficient Mice Develop Colitis and Bacteremia upon Infection with Normally Avirulent, TTSS-1- and TTSS-2-Deficient Salmonella Typhimurium
October 15, 2013 Boas Felmy, Pascal Songhet, Emma Slack, Andreas Müller, Marcus Kremer, Laurye Van Maele, Delphine Cayet, Mathias Heikenwalder, Jean-Claude Sirard, Wolf-Dietrich Hardt
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10.1371/journal.pone.0077894

PLOS ONE Proteomic Changes during B Cell Maturation: 2D-DIGE Approach
October 29, 2013 Johanna Salonen, Gunilla Rönnholm, Nisse Kalkkinen, Mauno Vihinen
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10.1371/journal.pone.0080131

PLOS ONE Occurrence of Nodular Lymphocyte-Predominant Hodgkin Lymphoma in Hermansky-Pudlak Type 2 Syndrome Is Associated to Natural Killer and Natural Killer T Cell Defects
November 26, 2013 Luisa Lorenzi, Giovanna Tabellini, William Vermi, Daniele Moratto, Fulvio Porta, Lucia Notarangelo, Ornella Patrizi, Silvano Sozzani, Genevieve de Saint basile, Sylvain Latour, David Pace, Silvia Lonardi, Fabio Facchetti, Raffaele Badolato, Silvia Parolini
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10.1371/journal.pone.0093180

PLOS ONE Serological Assessment for Celiac Disease in IgA Deficient Adults
April 7, 2014 Ning Wang, Lennart Truedsson, Kerstin Elvin, Bengt Andersson, Johan Rönnelid, Lucia Mincheva-Nilsson, Annica Lindkvist, Jonas Ludvigsson, Lennart Hammarström, Charlotte Dahle
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10.1371/journal.pone.0097571

PLOS ONE Gene Expression Profiling in Peripheral Blood Mononuclear Cells of Patients with Common Variable Immunodeficiency: Modulation of Adaptive Immune Response following Intravenous Immunoglobulin Therapy
May 15, 2014 Marzia Dolcino, Giuseppe Patuzzo, Alessandro Barbieri, Elisa Tinazzi, Monica Rizzi, Ruggero Beri, Giuseppe Argentino, Andrea Ottria, Claudio Lunardi, Antonio Puccetti
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10.1371/journal.pone.0100324

PLOS ONE Primary vs. Secondary Antibody Deficiency: Clinical Features and Infection Outcomes of Immunoglobulin Replacement
June 27, 2014 Sai Duraisingham, Matthew Buckland, John Dempster, Lorena Lorenzo, Sofia Grigoriadou, Hilary Longhurst
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10.1371/journal.pone.0103908

PLOS ONE Intravenous Immunoglobulin for Hypogammaglobulinemia after Lung Transplantation: A Randomized Crossover Trial
August 4, 2014 David Lederer, nisha philip, Debbie rybak, selim arcasoy, Steven Kawut

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