Research Analysis & Policy

Publishing Dual Use Research of Concern: A Case Study

Published October 4, 2018 Curated Collections

The implications of publishing dual use research of concern (DURC) continues to be a topic widely and deeply discussed in the scientific community. In a series of Opinion articles, PLOS Pathogens intends to contribute to this ongoing debate with four balanced and differing perspectives from notable members of the scientific community. The four author groups represented in these Opinions include Drs. Ryan S. Noyce and David H. Evans, two authors of a recent PLOS ONE study on Horsepox virus, Dr. Volker Thiel, who served as Academic Editor for the article describing the study, and Dr. Thomas Inglesby, Jr. and Dr. Kevin M. Esvelt, both of whom have advocated for changes in the peer reviewing and publishing of DURC-related research. These authors, use the PLOS ONE paper as a springboard for their Opinions.

Image Credit: History and pathology of vaccination, Edgar March Crookshank (1889)

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Research Article
Editorial
Opinions

Research Article

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10.1371/journal.pone.0188453

PLOS ONE Construction of an infectious horsepox virus vaccine from chemically synthesized DNA fragments
January 19, 2018 Ryan S. Noyce, Seth Lederman, David H. Evans

Editorial

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History and pathology of vaccination, Edgar March Crookshank (1889)

PLOS Pathogens Horsepox: Framing a dual use research of concern debate
October 4, 2018 Carolyn B. Coyne

Opinions

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Noyce RS, Evans DH (2018)

PLOS Pathogens Synthetic horsepox viruses and the continuing debate about dual use research
October 4, 2018 Ryan S. Noyce, David H. Evans
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Thiel V (2018)

PLOS Pathogens Synthetic viruses—Anything new?
October 4, 2018 Volker Thiel
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Esvelt KM (2018)

PLOS Pathogens Inoculating science against potential pandemics and information hazards
October 4, 2018 Kevin Esvelt
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Fred Murphy, Sylvia Whitfield, USCDCP

PLOS Pathogens Horsepox and the need for a new norm, more transparency, and stronger oversight for experiments that pose pandemic risks
October 4, 2018 Thomas Inglesby, Jr.

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