Genetically Modified Insect
The January 2012 issue of PLOS Neglected Tropical Diseases presented an Editorial, a Viewpoint, and two accompanying Expert Commentaries that focussed on the application of genetically modified (GM) insects for control of animal and plant diseases. These articles describe the technological advances these tools represent, the regulatory framework, and the societal dialogue that is necessary for their wide-scale application for disease control. Here, we have assembled a collection of articles published in the PLOS journals that describe the technical and applied aspects of GM insects. We also included articles that are not strictly GM, but aim to modify the disease transmission traits of insects through the use of symbiotic microbes.
Image Credit: James Gathany, Centers for Disease Control and Prevention
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PLOS Neglected Tropical Diseases Appropriate Regulation of GM Insects
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PLOS Neglected Tropical Diseases Science, Regulation, and Precedent for Genetically Modified Insects
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PLOS Neglected Tropical Diseases Scientific Standards and the Regulation of Genetically Modified Insects
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PLOS Neglected Tropical Diseases Human Probing Behavior of Aedes aegypti when Infected with a Life-Shortening Strain of Wolbachia
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PLOS Neglected Tropical Diseases A Virulent Wolbachia Infection Decreases the Viability of the Dengue Vector Aedes aegypti during Periods of Embryonic Quiescence
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PLOS Neglected Tropical Diseases piggybac– and PhiC31-Mediated Genetic Transformation of the Asian Tiger Mosquito, Aedes albopictus (Skuse)
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PLOS Neglected Tropical Diseases Strategies for Introducing Wolbachia to Reduce Transmission of Mosquito-Borne Diseases
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PLOS Pathogens Engineered Anopheles Immunity to Plasmodium Infection