Medicine & Health

Project SOAR: robust evidence to improve the global HIV response

Published August 25, 2020 Partnered Collections, Special Issues

Recent advances in the global HIV response hold great promise for ending the epidemic. Project SOAR implementation science research generates insights to inform and improve the provision of life-saving HIV prevention and treatment. This Special Collection presents SOAR research that evaluates innovative service delivery approaches, models cost and impact, and elucidates social barriers to care.

Image Credit: Kate Gannett Merrill, Johns Hopkins University

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Introduction
Project SOAR Research

Introduction

Image credit
Kate Gannett Merrill, Johns Hopkins University

PLOS Collections Blog Introducing Project SOAR’s HIV Implementation Science Research Collection: Timely Evidence to Guide the HIV Response – PLOS Collections
June 8, 2020 Scott Geibel, Eileen Yam

Project SOAR Research

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10.1371/journal.pone.025703 CC BY 4.0

PLOS ONE What are we learning about HIV testing in informal settlements in KwaZulu-Natal, South Africa? Results from a randomized controlled trial
March 8, 2022 Stephanie R. Psaki, Julie Pulerwitz, Brady Zieman, Paul C. Hewett, Mags Beksinska

Background: Recent evidence highlighting high HIV incidence and prevalence in informal settlements suggests that they are environments that…
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10.1371/journal.pone.0256256 CC BY 4.0

PLOS ONE A randomized controlled trial evaluating the effects of a family-centered HIV care model on viral suppression and retention in care of HIV-positive children in Eswatini
August 24, 2021 Kim Ashburn, Caspian Chouraya, Philisiwe Khumalo, Lydia Mpango, Nobuhle Mthethwa, Rhoderick Machekano, Laura Guay, Lynne M. Mofenson

Introduction: A family-centered care model (FCCM) providing family-based HIV services, rather than separate adult/pediatric services, has…
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10.1371/journal.pone.1003780 CC BY 4.0

PLOS Medicine Community-facility linkage models and maternal and infant health outcomes in Malawi’s PMTCT/ART program: A cohort study
September 17, 2021 Michael E. Herce, Maganizo B. Chagomerana, Lauren C. Zalla, Nicole B. Carbone, Benjamin H. Chi, Michael T. Eliya, Sam Phiri, Stephanie M. Topp, Maria H. Kim, Emily B. Wroe, Chileshe Chilangwa, Jacqueline Chinkonde, Innocent A. Mofolo, Mina C. Hosseinipour, Jessie K. Edwards

Background: In sub-Saharan Africa, 3 community-facility linkage (CFL) models—Expert Clients, Community Health Workers (CHWs), and Mentor…
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10.1371/journal.pone.0248751 CC BY 4.0

PLOS ONE HIV risk screening and HIV testing among orphans and vulnerable children in community settings in Tanzania: Acceptability and fidelity to lay-cadre administration of the screening tool
March 25, 2021 Michelle M. Gill, Ola Jahanpour, Roland van de Ven, Asheri Barankena, Peris Urasa, Gretchen Antelman

Introduction: HIV risk screening tool validation studies have not typically included process evaluations to understand tool implementation.…
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Antiretroviral Drugs to Treat HIV Infection by NIAID, CC BY 2.0

PLOS ONE Effects of the implementation of the HIV Treat All guidelines on key ART treatment outcomes in Namibia
December 28, 2020 Lung Vu, Brady Burnett-Zieman, Lizl Stoman, Minh Luu, Johnface Mdala, Krista Granger, Steven Forsythe, Abeje Zegeye, Scott Geibel

Background: This study aimed to help the Namibian government understand the impact of Treat All implementation (started on April 1, 2017)…
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10.1371/journal.pone.0237084

PLOS ONE Gaining traction: Promising shifts in gender norms and intimate partner violence in the context of a community-based HIV prevention trial in South Africa
August 20, 2020 Ann Gottert, Julie Pulerwitz, Nicole Haberland, Rhandzekile Mathebula, Dumisani Rebombo, Kathryn Spielman, Rebecca West, Aimée Julien, Rhian Twine, Dean Peacock, Mi-Suk Kang Dufour, F. Xavier Gómez-Olivé, Audrey Pettifor, Sheri A. Lippman, Kathleen Kahn
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10.1371/journal.pone.0235739

PLOS ONE Safer conception for female sex workers living with HIV in Dar es Salaam, Tanzania: Cross-sectional analysis of needs and opportunities in integrated family planning/HIV services
July 21, 2020 Eileen A. Yam, Catherine Kahabuka, Gaspar Mbita, Koheleth Winani, Louis Apicella, Caterina Casalini, Zuhura Mbuguni
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10.1371/journal.pone.0233590

PLOS ONE Active pediatric HIV case finding in Kenya and Uganda: A look at missed opportunities along the prevention of mother-to-child transmission of HIV (PMTCT) cascade
June 2, 2020 Michelle Gill, Eliab Natumanya, Heather Hoffman, Gordon Okomo, Geoffrey Taasi, Laura Guay, Rose Masaba
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NIAID, Flickr

PLOS ONE The impact of an integrated depression and HIV treatment program on mental health and HIV care outcomes among people newly initiating antiretroviral therapy in Malawi
May 6, 2020 Melissa A. Stockton, Michael Udedi, Kazione Kulisewa, Mina C. Hosseinipour, Bradley N. Gaynes, Steven M. Mphonda, Joanna Maselko, Audrey E. Pettifor, Ruth Verhey, Dixon Chibanda, Ilana Lapidos-Salaiz, Brian W. Pence
Image credit
NIAID, Flickr

PLOS ONE “It is always better for a man to know his HIV status” – A qualitative study exploring the context, barriers and facilitators of HIV testing among men in Nairobi, Kenya
April 15, 2020 Jerry Okal, Daniel Lango, James Matheka, Francis Obare, Carol Ngunu-Gituathi, Mary Mugambi, Avina Sarna
Image credit
10.1371/journal.pone.0228135

PLOS ONE The short-term effects of the implementation of the “Treat All” guidelines on ART service delivery costs in Namibia
January 27, 2020 Carl Schutte, Johnface Fedes Mdala, Brady Zieman, Rachael Linder, Lung Vu, Steven Forsythe
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10.1371/journal.pone.0223426

PLOS ONE The impact of PEPFAR transition on HIV service delivery at health facilities in Uganda
October 9, 2019 Jess Alan Wilhelm, Mary Qiu, Ligia Paina, Elizabeth Colantuoni, Moses Mukuru, Freddie Ssengooba, Sara Bennett
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10.1371/journal.pone.0228634

PLOS ONE The uptake of population size estimation studies for key populations in guiding HIV responses on the African continent
February 26, 2020 Nikita Viswasam, Carrie E. Lyons, Jack MacAllister, Greg Millett, Jennifer Sherwood, Amrita Rao, Stefan D. Baral, on behalf of the Global.HIV Research Group
Image credit
10.1371/journal.pone.0230703

PLOS ONE Project YES! Youth Engaging for Success: A randomized controlled trial assessing the impact of a clinic-based peer mentoring program on viral suppression, adherence and internalized stigma among HIV-positive youth (15-24 years) in Ndola, Zambia
April 2, 2020 Julie A. Denison, Virginia M. Burke, Sam Miti, Bareng A. S. Nonyane, Christiana Frimpong, Katherine G. Merrill, Elizabeth A. Abrams, Jonathan K. Mwansa

PLOS Partnership

Led by the Population Council in partnership with Avenir Health, Elizabeth Glaser Pediatric AIDS Foundation, Johns Hopkins University, Palladium, and The University of North Carolina at Chapel Hill, Project SOAR (Supporting Operational AIDS Research) is a six-year initiative that consists of more than 70 research activities in 24 countries.

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Funding Information

Project SOAR (Cooperative Agreement AID-OAA-A-14-00060) is made possible by the generous support of the American people through the President’s Emergency Plan for AIDS Relief and the United States Agency for International Development (USAID).