Background: In South America the sand fly Lutzomyia longipalpis is the predominant vector of Leishmania infantum, the parasite that causes…
Medicine & Health
Innovations for the Elimination and Control of Visceral Leishmaniasis Collection
"Through the suggestions and kind support of various stakeholders, we will continue in our efforts towards the sustained elimination of VL from the ISC and improved control in East Africa as a goal by continued networking, conducting meetings, monitoring progress, updating information via publications, including publications in PLOS Neglected Tropical Diseases, until we have the tools, the health system structure, and funding to ensure elimination of VL based upon sustainable interruption of transmission."
--Angamuthu Selvapandiyan, Guest Editor, PLOS Neglected Tropical Diseases
In this collection, PLOS Neglected Tropical Diseases presents a range of articles delving into the latest research into the elimination and control of visceral leishmaniasis.
Image Credit: Visceral leishmaniasis: lymph node by SB Lucas, https://creativecommons.org/share-your-work/public-domain/cc0/
PLOS Neglected Tropical Diseases
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PLOS Neglected Tropical Diseases Synthetic sex-aggregation pheromone of Lutzomyia longipalpis, the South American sand fly vector of Leishmania infantum, attracts males and females over long-distance
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PLOS Neglected Tropical Diseases Potential of Artesunate in the treatment of visceral leishmaniasis in dogs naturally infected by Leishmania infantum: Efficacy evidence from a randomized field trial
Leishmaniasis is among the world’s most neglected diseases. Dogs are the main reservoirs/hosts of Leishmania infantum, causative agent of…
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PLOS Neglected Tropical Diseases Sand fly synthetic sex-aggregation pheromone co-located with insecticide reduces the incidence of infection in the canine reservoir of visceral leishmaniasis: A stratified cluster randomised trial
Objective: To evaluate the efficacy of a synthetic sex-aggregation pheromone of the sand fly vector Lu. longipalpis, co-located with…
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PLOS Neglected Tropical Diseases Attraction of Lutzomyia longipalpis to synthetic sex-aggregation pheromone: Effect of release rate and proximity of adjacent pheromone sources
In South America, the Protist parasite that causes visceral leishmaniasis, a potentially fatal human disease, is transmitted by…
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PLOS Neglected Tropical Diseases Community deployment of a synthetic pheromone of the sand fly Lutzomyia longipalpis co-located with insecticide reduces vector abundance in treated and neighbouring untreated houses: Implications for control of Leishmania infantum
Background: The rising incidence of visceral leishmaniasis due to Leishmania infantum requires novel methods to control transmission by the…
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Image creditVisceral leishmaniasis: lymph node by SB Lucas, CC0PLOS Neglected Tropical Diseases Innovations for the elimination and control of visceral leishmaniasis
Visceral leishmaniasis (VL), a disease associated with poverty, is endemic in the Indian subcontinent and Africa...
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PLOS Neglected Tropical Diseases The human immune response to saliva of Phlebotomus alexandri, the vector of visceral leishmaniasis in Iraq, and its relationship to sand fly exposure and infection
Background: Sand fly saliva exposure plays an important role in immunity against leishmaniasis where it has mostly been associated with…
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PLOS Neglected Tropical Diseases Risk factors for antimony treatment failure in American Cutaneous Leishmaniasis in Northwestern-Argentina
Background. To date, there is no specific literature available on the determinants for therapeutic failure (TF) with meglumine antimoniate…
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PLOS Neglected Tropical Diseases The potential impact of human visceral leishmaniasis vaccines on population incidence
Human visceral leishmaniasis (VL) vaccines are currently under development and there is a need to understand their potential impact on…
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PLOS Neglected Tropical Diseases Urine-based antigen detection assay for diagnosis of visceral leishmaniasis using monoclonal antibodies specific for six protein biomarkers of Leishmania infantum / Leishmania donovani
The development of an accurate protein-based antigen detection assay for diagnosis of active visceral leishmaniasis (VL) would represent a…
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PLOS Neglected Tropical Diseases Role of asymptomatic and symptomatic humans as reservoirs of visceral leishmaniasis in a Mediterranean context
Background: In the Mediterranean basin, Leishmania infantum is the causative agent of visceral leishmaniasis (VL), a zoonosis in which the…
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PLOS Neglected Tropical Diseases A spatio-temporal approach to short-term prediction of visceral leishmaniasis diagnoses in India
Background: The elimination programme for visceral leishmaniasis (VL) in India has seen great progress, with total cases decreasing by over…
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PLOS Neglected Tropical Diseases Long-term incidence of relapse and post-kala-azar dermal leishmaniasis after three different visceral leishmaniasis treatment regimens in Bihar, India
Background: Few prospective data exist on incidence of post kala-azar dermal leishmaniasis (PKDL) and visceral leishmaniasis (VL) relapse…