Background: Plasmodium vivax has been proposed to infect and replicate in the human spleen and bone marrow. Compared to Plasmodium…
Vivax Malaria Collection
While great strides have been made in efforts to treat and prevent malaria caused by Plasmoidum falciparum, more progress is needed to address the unique challenges associated with preventing and treating malaria attributable to Plasmodium vivax. The papers within this Collection advance our understanding of what is known regarding the epidemiology of P. vivax malaria, and inform and discuss strategies for prevention, treatment, and elimination.
Image Credit: Preah Khan jungle temple, cambodia by Stig Berge, CC 0
-
PLOS Medicine Positron emission tomography and magnetic resonance imaging in experimental human malaria to identify organ-specific changes in morphology and glucose metabolism: A prospective cohort study
-
PLOS Medicine Global economic costs due to vivax malaria and the potential impact of its radical cure: A modelling study
Background: In 2017, an estimated 14 million cases of Plasmodium vivax malaria were reported from Asia, Central and South America, and the…
-
PLOS Medicine Evaluation of splenic accumulation and colocalization of immature reticulocytes and Plasmodium vivax in asymptomatic malaria: A prospective human splenectomy study
Background: A very large biomass of intact asexual-stage malaria parasites accumulates in the spleen of asymptomatic human individuals…
-
Image creditPlasmodium vivax 01 by CDC/ Steven Glenn, Laboratory & Consultation Division, CC 0PLOS Medicine Taking on Plasmodium vivax malaria: A timely and important challenge
Lorenz von Seidlein and Nicholas White introduce a Collection on Plasmodium vivax…
-
PLOS Medicine Glucose-6-phosphate dehydrogenase activity in individuals with and without malaria: Analysis of clinical trial, cross-sectional and case–control data from Bangladesh
Background: Glucose-6-phosphate dehydrogenase (G6PD) activity is dependent upon G6PD genotype and age of the red blood cell (RBC)…
-
PLOS Medicine Towards the elimination of Plasmodium vivax malaria: Implementing the radical cure
In this review for the Vivax malaria collection, Kamala Thriemer and colleagues explore efforts to eliminate P. vivax…
-
PLOS Medicine The changing epidemiology of Plasmodium vivax: Insights from conventional and novel surveillance tools
Sarah Auburn and co-authors discuss the unique biology and epidemiology of P. vivax and current evidence on conventional and new…
-
PLOS Medicine The prevention and treatment of Plasmodium vivax malaria
Cindy S Chu and co-authors review options for diagnosis, safe and radical cure, and relapse prevention of Plasmodium…
-
PLOS Medicine Estimated impact of tafenoquine for Plasmodium vivax control and elimination in Brazil: A modelling study
Background: Despite recent intensification of control measures, Plasmodium vivax poses a major challenge for malaria elimination efforts.…