Medicine & Health

Vivax Malaria Collection

Published April 23, 2021 Partnered Collections

While great strides have been made in efforts to treat and prevent malaria caused by Plasmoidum falciparum, more progress is needed to address the unique challenges associated with preventing and treating malaria attributable to Plasmodium vivax. The papers within this Collection advance our understanding of what is known regarding the epidemiology of P. vivax malaria, and inform and discuss strategies for prevention, treatment, and elimination.

Image Credit: Preah Khan jungle temple, cambodia by Stig Berge, CC 0

Jump to section

PLOS Medicine Collection

PLOS Medicine Collection

Image credit
10.1371/journal.pmed.1003567 CC BY 4.0

PLOS Medicine Positron emission tomography and magnetic resonance imaging in experimental human malaria to identify organ-specific changes in morphology and glucose metabolism: A prospective cohort study
May 26, 2021 John Woodford, Ashley Gillman, Peter Jenvey, Jennie Roberts, Stephen Woolley, Bridget E. Barber, Melissa Fernandez, Stephen Rose, Paul Thomas, Nicholas M. Anstey, James S. McCarthy

Background: Plasmodium vivax has been proposed to infect and replicate in the human spleen and bone marrow. Compared to Plasmodium…
Image credit
10.1371/journal.pmed.1003614 CC BY 4.0

PLOS Medicine Global economic costs due to vivax malaria and the potential impact of its radical cure: A modelling study
June 1, 2021 Angela Devine, Katherine E. Battle, Niamh Meagher, Rosalind E. Howes, Saber Dini, Peter W. Gething, Julie A. Simpson, Ric N. Price, Yoel Lubell

Background: In 2017, an estimated 14 million cases of Plasmodium vivax malaria were reported from Asia, Central and South America, and the…
Image credit
10.1371/journal.pmed.1003632 CC BY 4.0

PLOS Medicine Evaluation of splenic accumulation and colocalization of immature reticulocytes and Plasmodium vivax in asymptomatic malaria: A prospective human splenectomy study
May 26, 2021 Steven Kho, Labibah Qotrunnada, Leo Leonardo, Benediktus Andries, Putu A. I. Wardani, Aurelie Fricot, Benoit Henry, David Hardy, Nur I. Margyaningsih, Dwi Apriyanti, Agatha M. Puspitasari, Pak Prayoga, Leily Trianty, Enny Kenangalem, Fabrice Chretien, Valentine Brousse, Innocent Safeukui, Hernando A. del Portillo, Carmen Fernandez-Becerra, Elamaran Meibalan, Matthias Marti, Ric N. Price, Tonia Woodberry, Papa A. Ndour, Bruce M. Russell, Tsin W. Yeo, Gabriela Minigo, Rintis Noviyanti, Jeanne R. Poespoprodjo, Nurjati C. Siregar, Pierre A. Buffet, Nicholas M. Anstey

Background: A very large biomass of intact asexual-stage malaria parasites accumulates in the spleen of asymptomatic human individuals…
Image credit
Plasmodium vivax 01 by CDC/ Steven Glenn, Laboratory & Consultation Division, CC 0

PLOS Medicine Taking on Plasmodium vivax malaria: A timely and important challenge
April 23, 2021 Lorenz von Seidlein, Nicholas J. White

Lorenz von Seidlein and Nicholas White introduce a Collection on Plasmodium vivax…
Image credit
10.1371/journal.pmed.1003576

PLOS Medicine Glucose-6-phosphate dehydrogenase activity in individuals with and without malaria: Analysis of clinical trial, cross-sectional and case–control data from Bangladesh
April 23, 2021 Benedikt Ley, Mohammad Shafiul Alam, Mohammad Golam Kibria, Jutta Marfurt, Ching Swe Phru, Jenifar Quaiyum Ami, Kamala Thriemer, Sarah Auburn, Nusrat Jahan, Fatema Tuj Johora, Mohammad Sharif Hossain, Cristian Koepfli, Wasif Ali Khan, Ric N. Price

Background: Glucose-6-phosphate dehydrogenase (G6PD) activity is dependent upon G6PD genotype and age of the red blood cell (RBC)…
Image credit
10.1371/journal.pmed.100349

PLOS Medicine Towards the elimination of Plasmodium vivax malaria: Implementing the radical cure
April 23, 2021 Kamala Thriemer, Benedikt Ley, Lorenz von Seidlein

In this review for the Vivax malaria collection, Kamala Thriemer and colleagues explore efforts to eliminate P. vivax…
Image credit
10.1371/journal.pmed.1003560

PLOS Medicine The changing epidemiology of Plasmodium vivax: Insights from conventional and novel surveillance tools
April 23, 2021 Sarah Auburn, Qin Cheng, Jutta Marfurt, Ric N. Price

Sarah Auburn and co-authors discuss the unique biology and epidemiology of P. vivax and current evidence on conventional and new…
Image credit
10.1371/journal.pmed.1003561

PLOS Medicine The prevention and treatment of Plasmodium vivax malaria
April 23, 2021 Cindy S. Chu, Nicholas J. White

Cindy S Chu and co-authors review options for diagnosis, safe and radical cure, and relapse prevention of Plasmodium…
Image credit
10.1371/journal.pmed.1003535

PLOS Medicine Estimated impact of tafenoquine for Plasmodium vivax control and elimination in Brazil: A modelling study
April 23, 2021 Narimane Nekkab, Raquel Lana, Marcus Lacerda, Thomas Obadia, André Siqueira, Wuelton Monteiro, Daniel Villela, Ivo Mueller, Michael White

Background: Despite recent intensification of control measures, Plasmodium vivax poses a major challenge for malaria elimination efforts.…