Visceral Leishmaniasis and HIV Co-Infection
HIV has been identified as one of the emerging challenges for visceral leishmaniasis (VL) control. HIV infection dramatically increases the risk of progression from asymptomatic infection towards disease (VL) and VL accelerates HIV disease progression. Whereas HIV has contributed to the re-emergence of VL in Europe in the 90's, this problem is now increasingly being reported globally, and is especially severe in some areas of Eastern Africa, in particular north Ethiopia where up to 40% of patients with VL are co-infected with HIV. The problem is also on the rise in South-America and the Indian subcontinent. PLOS Neglected Tropical Diseases has dedicated this special collection to VL-HIV co-infection in collaboration with Johan van Griensven, Ed Zijlstra and Asrat Hailu.
Image Credit: Mock et al.
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PLOS Neglected Tropical Diseases Visceral Leishmaniasis as an AIDS Defining Condition: Towards Consistency across WHO Guidelines
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PLOS Neglected Tropical Diseases Visceral Leishmaniasis and HIV Coinfection in the Mediterranean Region
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PLOS Neglected Tropical Diseases Visceral Leishmaniasis and HIV Coinfection in East Africa
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PLOS Neglected Tropical Diseases Leishmania-HIV Co-infection: Clinical Presentation and Outcomes in an Urban Area in Brazil
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PLOS Neglected Tropical Diseases High Parasitological Failure Rate of Visceral Leishmaniasis to Sodium Stibogluconate among HIV Co-infected Adults in Ethiopia
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PLOS Neglected Tropical Diseases MicroRNA Expression Profile in Human Macrophages in Response to Leishmania major Infection
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PLOS Neglected Tropical Diseases Arginase Activity in the Blood of Patients with Visceral Leishmaniasis and HIV Infection
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PLOS Neglected Tropical Diseases Predictors of Visceral Leishmaniasis Relapse in HIV-Infected Patients: A Systematic Review