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Biology & Life Sciences

Diagnostic Tests in Low-Resource Settings

Curated Collections

Advances in technology and engineering over the past few decades have led to an increased interest in developing new, low-cost diagnostic techniques for use in resource-constrained settings. This Collection showcases recent advances in initial laboratory experiments and technology development as well as in-field clinical applications of these technologies.

Submit your research to PLOS ONE, PLOS Biology, PLOS Pathogens, PLOS Digital Health, PLOS Global Public Health, PLOS Neglected Tropical Diseases or PLOS Water to feature your research in this collection.

Image Credit: George Hodan

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    Translational Research in the Time of COVID-19—Dissolving Boundaries

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    Coronavirus by Yuri Samoilov, CC BY 2.0
    Multiplex qPCR discriminates variants of concern to enhance global surveillance of SARS-CoV-2

    With the emergence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) variants that may increase transmissibility and/or…

  • CombiANT: Antibiotic interaction testing made easy

    Antibiotic combination therapies are important for the efficient treatment of many types of infections, including those caused by…

  • A sensitive and affordable multiplex RT-qPCR assay for SARS-CoV-2 detection

    With the ongoing COVID-19 (Coronavirus Disease 2019) pandemic, caused by the novel coronavirus SARS-CoV-2 (Severe Acute Respiratory…

  • Rapid detection of SARS-CoV-2 with CRISPR-Cas12a

    The recent outbreak of betacoronavirus Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), which is responsible for the…

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    Detection of SARS-CoV-2 RNA by multiplex RT-qPCR
  • Direct RT-qPCR detection of SARS-CoV-2 RNA from patient nasopharyngeal swabs without an RNA extraction step
  • Machine learning of human plasma lipidomes for obesity estimation in a large population cohort

    Obesity is associated with changes in the plasma lipids. Although simple lipid quantification is routinely used, plasma lipids are rarely…

  • Resistance diagnostics as a public health tool to combat antibiotic resistance: A model-based evaluation

    Rapid point-of-care resistance diagnostics (POC-RD) are a key tool in the fight against antibiotic resistance. By tailoring drug choice to…

  • Rapid ultrasensitive detection platform for antimicrobial susceptibility testing

    Rapid detection and phenotyping of pathogenic microbes is critical for administration of effective antibiotic therapies and for impeding…

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    Surveillance to maintain the sensitivity of genotype-based antibiotic resistance diagnostics

    The sensitivity of genotype-based diagnostics that predict antimicrobial susceptibility is limited by the extent to which they detect…

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Read the latest COVID-19 research articles from a range of the PLOS journals.

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