The Signaling Pathways Project is a multi-omics knowledgebase based upon public, manually curated transcriptomic and cistromic (ChIP-Seq) datasets involving genetic and small molecule manipulations of…
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Biology & Life Sciences Structural Biology & Human Health: Medically Relevant Proteins from the SGCView Collection
This collection of articles represents some of the research highlights from the Structural Genomics Consortium (SGC). The SGC is an international public-private partnership that determines three…
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Biology & Life Sciences RECOMB Regulatory Genomics and Systems Biology 2009View Collection
In a joint venture between PLOS and the conference program committee, this collection draws together papers from the 6th Annual RECOMB Satellite on Regulatory Genomics and the 5th Annual RECOMB…
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Research Analysis & Policy Animals, Research, and Alternatives: Measuring Progress 50 Years LaterView Collection
In 2010, a multi-disciplinary, international conference in Washington, DC addressed opportunities and challenges to implementing alternatives to animal research. This symposium aimed to advance the…
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Computer & Information Sciences Proceedings of the Third International Barcode of Life Conference Mexico CityView Collection
"DNA barcoding" was proposed formally in 2003 as a technique for species diagnosis and identification using short standardized gene regions. Early conferences focused on the degree to which…
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Biology & Life Sciences The DREAM Systems Biology ChallengesView Collection
The Dialogue for Reverse Engineering Assessments and Methods (DREAM) grew as a community effort to catalyze discussion about the design, application, and assessment of systems biology models through…
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Biology & Life Sciences The World Register of Marine SpeciesView Collection
This collection has been created by the editors of the World Register of Marine Species (WoRMS), an open-access online database which holds information on all marine species, and some of their…
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Biology & Life Sciences Epigenetics 2010View Collection
Epigenetics is the study of inherited changes in phenotype or gene expression caused by mechanisms other than changes in the underlying DNA sequence. This collection brings together twenty research…
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Biology & Life Sciences The Human Microbiome ProjectView Collection
The healthy adult body hosts ten times as many microbial cells as human cells.The metagenome carried collectively by these microbial communities dwarfs the human genome in size, and their influences…
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Medicine & Health Real-Time Monitoring of Under-Five MortalityView Collection
In most low-income countries, Ministries of Health and their partners must rely on periodic household surveys as their primary population-level source of vital statistics. Recent initiatives around…
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Medicine & Health malERA – An updated research agenda for malaria elimination and eradicationView Collection
‘malERA Refresh’ is a forward-looking research and development agenda that accelerates progress towards malaria elimination and global eradication. The malERA Refresh special collection…